2. Signaling Pathways
  3. GPCR/G Protein
  4. Protease Activated Receptor (PAR)
  5. Protease Activated Receptor (PAR) Agonist

Protease Activated Receptor (PAR) Agonist

Protease Activated Receptor (PAR) Isoform Comparison

Protease Activated Receptor (PAR) Agonists (37):

Cat. No. Product Name Effect Purity
  • HY-P0078
    TRAP-6
    		Agonist 99.84%
    TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4.
  • HY-P1314
    2-Furoyl-LIGRLO-amide
    		Agonist 99.87%
    2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0..
  • HY-P1308
    SLIGRL-NH2
    		Agonist 99.98%
    SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2).
  • HY-P1309A
    PAR-4 Agonist Peptide, amide TFA
    		Agonist 99.70%
    PAR-4 Agonist Peptide, amide TFA (PAR-4-AP TFA; AY-NH2 TFA) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.
  • HY-P0283
    Protease-Activated Receptor-2, amide
    		Agonist 98.73%
    Protease-Activated Receptor-2, amide (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.
  • HY-P1309
    PAR-4 Agonist Peptide, amide
    		Agonist 99.48%
    PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.
  • HY-120528A
    GB-110 hydrochloride
    		Agonist 99.86%
    GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM.
  • HY-P0226A
    TFLLR-NH2(TFA)
    		Agonist 99.78%
    TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM.
  • HY-14350
    AC-55541
    		Agonist 99.25%
    AC-55541 is a highly selective protease-activated receptor 2 (PAR2) agonist (pEC50=6.7), displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. AC-55541 has pEC50 values of 5.9 and 6.6 in PI hydrolysis assays and Ca2+ mobilization assays and exhibits pronociceptive activity in vivo.
  • HY-P4803
    PAR-2 (1-6) (human)
    		Agonist 99.49%
    PAR-2 (1-6) (human) (SLIGKV), a peptide ligand, is a PAR-2 agonist.
  • HY-P0297
    Protease-Activated Receptor-4
    		Agonist
    Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).
  • HY-P2519A
    Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
    		Agonist 99.86%
    Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a proteinase-activated receptor (PAR-3) agonist peptide.
  • HY-P2518
    Protease-Activated Receptor-1, PAR-1 Agonist
    		Agonist 98.34%
    Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor.
  • HY-P2518A
    Protease-Activated Receptor-1, PAR-1 Agonist TFA
    		Agonist 98.54%
    Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor.
  • HY-P5001
    iso-TRAP-6
    		Agonist 99.26%
    iso-TRAP-6 (iso-SFLLRN) is a PAR-1 agonist that can activate platelets. iso-TRAP-6 is an analog of TRAP-6 (HY-P0078) that refers to the use of isoserine instead of serine as first amino acid.
  • HY-14351
    AC-264613
    		Agonist 98.3%
    AC-264613 is a potent and selective protease-activated receptor (PAR-2) agonist with a pEC50 of 7.5.
  • HY-P1310
    VKGILS-NH2
    		Agonist 99.81%
    VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells.
  • HY-P1261A
    Parstatin(mouse) TFA
    		Agonist 99.71%
    Parstatin(mouse) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis.
  • HY-P5360
    TFLLRN-NH2
    		Agonist 99.34%
    TFLLRN-NH2 is a biological active peptide. (PAR-1 Agonist)
  • HY-P2321
    TRAP-6 amide
    		Agonist 98.12%
    TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.